Sally was born on May 26, 1959, with Charlie Brown receiving a telephone call from the hospital and dashing out of the house yelling that he had a new baby sister.[5] She was given the name "Sally" on June 2, 1959. Although Sally was often talked about and was the cause for a celebration that included Charlie Brown passing out chocolate cigars, it was not until August 23, 1959, that she finally made her first appearance in the strip.
Like other characters, such as Linus and Schroeder (who were also introduced to the strip as babies), Sally grew up quickly. The week of August 22, 1960, she took her first steps, and developed a lasting crush on Linus.
Sally went to kindergarten for the first time in a three-week sequence from August 20 to September 7, 1962.
It was originally Linus who expressed a possible romantic interest in Sally. In a strip appearing shortly after Sally's birth, Linus is seen scribbling calculations on a fence. When Charlie Brown wanders by, Linus asks him, "When I'm 22 and Sally is 17, do you think she'll go out with me?"
In a storyline which began on November 29, 1965, Sally was diagnosed with amblyopia ex anopsia (lazy eye) which required her to wear an eye patch for a while.
In September 1974, Sally started talking to her school building, expressing her fears and concerns about going to school.[10] The building would answer back in thought bubbles, although Schulz's intention was that Sally could not hear these replies.