Stan Marsh	Kyle Broflovski

De facto protagonist. He and Kyle are best friends	The only Jewish in town besides his brother. Cartman is his biggest enemy.
"Oh my God, they killed Kenny!" →	You bastards!
Eric Cartman	Kenny McCormick

He is a fat racist with a super villainous, douchebag personality.	The poor kid and a walking death flag.
"I'm not fat, I'm big-boned!"	"Mrrph rmph rmmph mrrphh!"

Children

Classmates

Boys

Butters Stotch

A Quasi-major character who is mainly pushed around by the four main characters.
"Well Hey Fellas!"

Craig's Gang (Craig and Those Guys)

Craig Tucker	Tweak Tweak

A troubled boy who has a habit of holding up his middle finger at others.	A boy who is addicted to caffeine and often shakes.
"If could say titty sprinkles on national television, I would be soooo happy."	"I can't stand this kind of pressure!"
Clyde Donovan	Tolkien Black (Token Williams)

A little crybaby boy of Dutch American descent	A very rich black kid. He is a very good singer.
Jimmy Valmer

A kid with muscular dystrophy who walks constantly on crutches.
"What a terrific audience."

Timmy Burch	Scott Malkinson

A boy in a wheelchair with a severe mental disability.	Made fun by the other kids for his lisp and diabetes.
"Timmy!	"I'm Scott Malkinson."
Bradley Biggle	Kevin Stoley

Adopted brother of Henrietta.	Chinese American boy and Star Trek fan.
"Shablagoo!"
Bill Allen and Fosse McDonald

Parody characters of Beavis and Butt-head.

David Rodriguez: Latino American boy.
DogPoo Petuski: A character based off of Pig-Pen from Peanuts.
Brimmy: A character that been around since season 1.

Girls

Wendy Testaburger

Stan's on again, off again girlfriend and honor student. She is shown to be very political.

Bebe Stevens	Red McArthur

Wendy's best friend and the "popular" girl.	Wendy and Bebe's friend, a red-haired girl.
Heidi Turner	Nichole Daniels

Cartman's ex-girlfriend.	An African American girl and Tolkien's girlfriend.
Lola	Jenny Simons

Jenny's best friend.	Lola's best friend.
Annie Knitts	Millie Larsen

A girl with blonde curly hair.	A girl with a southern accent.
Esther	Nellie

Millie's and Annie's friend.	Aggressive girl.
Leslie Meyers	Sophie Gray

The main antagonist of season nineteen.	A girl with diabetes.

Other Classes, Grades, Etc.

Goth Kids

A group of four people who wear and believe in gothic clothing and behavior. They often hang out in the back of the school. They make up of (left to right) Pete Thelman, Michael, Henrietta Biggle, and Firkle Smith.

Damien Thorn	Scott Tenorman

Son of Satan. From the seventh level of hell.	He had bad a confrontation with Cartman.
Gregory	Christophe

Movie only character that leads La Resistance	Infiltration expert and always shown smoking a cigarette (Also movie only character).
Nathan	Mimsy

A boy with Down Syndrome and rival of Jimmy.	A boy who suffers from a mental disorder. Nathan is his boss.
"Shut up! Mimsy!"→	"Sorry Boss!"
The New Kid

A video game only character. The player's character

Faculty

Mr. Garrison	Principal PC

Homeroom teacher and homosexual who has many many psychological problems.	As his name suggests, he is very sensitive to PC and is the principal.
Mr. Mackey	Strong Woman

Counselor with a big head whose signature phrase is "m'kay".	A woman hired as an assistant principal to deal with a bullying problem.

Principal Victoria - Former principal.

Heroes

Coon and Friends and Freedom Pals	Super Best Friends

A group of 4th grade heroes who protect the city.	Heroes of gods, Buddha, and religious figures from various countries.

Children's Families

The Marshs (Stan's family)

Randy Marsh	Sharon Marsh

Officially voted #1 douchebag father. He is currently working as a geologist.	As a mother, she treats Stan gently and sometimes harshly. She works as a receptionist at Tom's Rhinoplasty
Shelly Marsh	Marvin Marsh

A violent older sister calling others as "turds". She wears a orthodontic headgear.	A 102 year old grandfather. In the early days, he often asked to be killed. He calls Stan "Billy" for some reason. But he seems to recognize Stan as his grandson.
Sparky	Jimbo Kern

The family dog, part doberman and part wolf	Vietnam veteran, and an avid gun enthusiast.

The Broflovskis (Kyle's family)

Gerald Broflovski	Sheila Broflovski

A father who has recently become more and more out of control and has been acting strangely.	An educated mother. Her temper tantrums and anger are characteristic of her. Even so, she loves her sons.
Ike Broflovski	Kyle Schwartz

A genius kindergartner, adopted brother and Canadian. He often gets "kick the baby" by Kyle.	He has heavy breathing due to asthma and also has poor eyesight.
"Don't kick the baby!"

The Cartmans (Cartman's family)

Liane Cartman	Mr. Kitty

a quiet woman, but in her true nature she is very sexually active. Recently, she's started to be stricter with Cartman's discipline, but she's definitely more lenient than the other parents.	The family cat, due to many pronouns, Mr. Kitty was revealed to be intersex in a FAQ.

The McCormicks (Kenny's family)

Stewart McCormick	Caroline McCormick

A father who almost never works and drinks all the time. He has been best friends with Gerald Brofloski since childhood but had a falling out.	She and her husband fight a lot and she works to earn money.
Kevin McCormick	Karen McCormick

Appears infrequently. He once had a big fight with his father.	She is close to Kenny and trusts Mysterion.

The Stotchs (Butters' family)

Steven Stotch	Linda Stotch

A father who is very presumptive and often gets his son grounded.	Like her husband, she is basically an unreasonably strict mother to her only son (although she is more lenient than her husband).

Other Characters

Santa Claus	Woodland Critters

Santa Claus himself. He usually lives in the North Pole.	deceptively cute, but truly evil satanic animals imagined by Eric.
Mr. Hankey	Towelie

A sentient piece of poo and a Christmas deity.	A sentient towel that gives towel advice and addicted to many drugs.
"Howdy Ho!"	"Wanna Get High?"
Terrence & Phillip	Ned Gerblanski

Canadian comedy duo. Prefer fart jokes.	Worked with Jimbo in the Vietnam War and lost his right arm. Talks through an electrolarynx.
Harrison Yates	Officer Barbrady

Sergeant at the South Park Police Department.	Incompetent policeman who protects the public safety of South Park. He once went to school with Stan and the other four idiots because he couldn't read.
Tuong Lu Kim	Satan

He owner of a Chinese restaurant City Wok.	The ruler of hell. He died after losing a battle to ManBearPig.
ManBearPig	Big Gay Al

A demon summoned from hell.	A gay man known for his flamboyant and positive demeanor.
Mr. Slave	Father Maxi

Al's husband and Mr. Garrison's ex-boyfriend.	A priest in the Catholic Church. He is thoroughly critical of pedophilia.
Thomas	Mayor McDaniels

A boy with tourette syndrome.	The mayor of South Park.

Deceased Characters

Chef

A black man who worked as a cook in the cafeteria of the elementary school. He is one of the few adults in South Park who has common sense, and is often asked by the students for advice, warning them when their behavior is inappropriate.

Pip Pilip

A transfer student from England. In the 200th episode of the 14th season, he was trampled to death by the giant robot Mecha-Streisand.

Jason White

A background character, but in season 23, episode 6 season finale when he goes into the street to receive a pass during football practice with everyone he went into the street to receive a pass and was hit by a police car and died.

Veronica Crabtree (Ms. Crabtree)

Driver of the South Park Elementary School shuttle bus. When she picks up students, she says "Sit down and shut up!". She was slaughtered by a serial killer in season 8, episode 13 because of her lack of appearance.

Alter Egos

Mysterion	Professor Chaos

A mysterious hero appears out of nowhere. His true identity is Kenny. Based off of Batman.	Butters' supervillain alter-ego. Based off of Thanos.
"I’m an angel keeping watch over the city at night."	"Mwahaha!"
Princess Kenny	Marjorine

Kenny's princess alter-ego. Based off of Zelda.	Butters disguise for getting into a girl's sleepover.
"プリンセスケニーレポート！" ("Princess Kenny is reporting!")
A.W.E.S.O.M.-O 4000	Mr. Hat

Cartman's toy robot disguise to prank Butters	Part of Mr. Garrison's psychological problems. He was use as a teaching assistan.